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Chen Li-Li

姓  名:陳歷歷
現  職:國立臺灣海洋大學海洋生物研究所教授               
               國立臺灣海洋大學海洋生物科技博士學位學程教授
校內分機:(02) 24622192 ext 5302 (辦公室)、5312 (實驗室)
傳  真:(02) 2463-3152
電子信箱:joechen@ntou.edu.tw
學  歷:國立臺灣大學動物學研究所博士
研究專長:動物學、微生物學、水產病毒學、分子生物學
任教課程:分子生物學、水族類疾病特論
研 究 室:甲殼類病毒學及免疫學研究室
近五年研究計畫pdf檔案、學術性著作pdf檔案

 

近五年期刊論文(Publications)

2022

1. Budi, Y. P., Lin, L. C., Chung, C. H., Chen, L. L., Jiang, Y. F.* (2022) Three-dimensional investigations of virus-associated structures in the nuclei with white spot syndrome virus (WSSV) infection in red swamp crayfish (Procambarus clarkii). Animals 12(13), 1730. DOI:10.3390/ani12131730

2. Hsu, J. C. K.#, Huang, H. T.#, Lin, H. J., Chou, H. Y., Huang, P. Y., Prachumwat, A.* and Chen, L. L.* (2022). Applying modified VP53A recombinant protein as an anti-white spot syndrome virus biological agent in Litopenaeus vannamei farming. Viruses 14(7), 1353. DOI: 10.3390/v14071353

3. Hsu, J. C. K., Hsu, T. K., Kannan, J., Wang, H. C., Tassanakajon, A. and Chen, L. L.* (2022). Diagnostic performance of a rapid test kit for white spot syndrome virus (WSSV). Aquaculture 558, 738379. DOI: 10.1016/j.aquaculture.2022.738379

2021

1. Yen, S. C., Mao, J. Y., Lin, H. Y., Huang, H. T., Harroun, S. G., Nain, A., Chang, H. T., Lin, H. Y., Chen, L. L., Huang, C. C.* and Lin, H. J. (2021). Multifunctional carbonized nanogels to treat lethal acute hepatopancreatic necrosis disease. Journal of Nanobiotechnology 19(1), 448. DOI: 10.1186/s12951-021-01194-8.

2. Huang, P. Y., Huang, Y. H., Leu, J. H. and Chen, L. L.* (2021). Feasibility study on the use of fly maggots (Musca domestica) as carriers to inhibit shrimp white spot syndrome. Life 11(8), 818. DOI: 10.3390/life11080818.

3. Lee, P. T., Huang, J., Huang, C. Y., Liu, Z. X., Yeh, H. Y., Huang, H. T., Chen, L. L., Nan, F. H. and Lee, M. C.* (2021). Phycoerythrin from Colaconema sp. has immunostimulatory effects on the whiteleg shrimp Litopenaeus vannamei and increases resistance to Vibrio parahaemolyticus and white spot syndrome virus. Animals 11(8), 2371. DOI: 10.3390/ani11082371

4. Ma, C. H. #, Huang, P. Y. #, Chang, Y. C., Pan, Y. J., Azra, M. N., Chen, L. L., and Hsu, T. H.* (2021). Improving survival of juvenile scalloped spiny lobster (Panulirus homarus) and crucifix crab (Charybdis feriatus) using shelter and live prey. Animals 11(2), 370. DOI: 10.3390/ani11020370

2020

1. Huang, P. Y., Hsiao, H. C., Wang, S. W., Lo, S. F., Lu, M. W. and Chen, L. L.* (2020). Screening for the proteins that can interact with grouper nervous necrosis virus capsid protein. Viruses, 12(9), 985. DOI: 10.3390/v12090985

2. Huang, H. T., Lin, H. J., Huang, H. J., Huang, C. C., Lin, J. H. Y.* and Chen, L. L.* (2020). Synthesis and evaluation of polyamine carbon quantum dots (CQDs) in Litopenaeus vannamei as a therapeutic agent against WSSV. Scientific Reports 10, 7343. DOI: 10.1038/s41598-020-64325-5

2017

1. Lee, Y. J. and Chen, L. L.* (2017). WSSV envelope protein VP51B links structural protein complexes and may mediate virus infection. Journal of Fish Diseases 40(4), 571-581. DOI: 10.1111/jfd.12538

2015

1. Lu, J. K.*, Chou, H. Y., Gong, H. Y., Chiou, P. P., Huang, C. W., Chen, L. L. and Wu, J. L. (2015). The marine aquaculture biotechnology status and its sustainability in Taiwan. Current Biotechnology 4(3), 311-318. DOI: 10.2174/2211550104666151016203821

2. Huang, H. T., Chan, H. L., Shih, T. Y. and Chen, L. L.* (2015). A study of the role of glucose transporter 1 (Glut1) in white spot syndrome virus (WSSV) infection. Fish and Shellfish Immunology 46(2), 305-314. DOI: 10.1016/j.fsi.2015.06.034

3. Lin, Y. C., Chen, J. C.*, Chen, Y. Y., Yeh, S. T., Chen, L. L., Huang, C. L., Hsieh, J. F. and Li, C. C. (2015). Crowding of white shrimp Litopenaeus vananmei depresses their immunity to and resistance against Vibrio alginolyticus and white spot syndrome virus. Fish and Shellfish Immunology 45(1), 104-111. DOI: 10.1016/j.fsi.2015.02.012

近五年研討會論文(Conference posters or papers)

2020

1. Chen, L. L.* and Huang, P. Y. (2020). Screening for the proteins that can interact with grouper nervous necrosis virus capsid protein. International Conference On Marine Science and Aquaculture (icomsa), virtual. Dec 9-10.

2. Chen, L. L.* (2020). Screening for proteins that can interact with grouper nervous necrosis virus (NNV) coat protein. Aquaculture America 2020, Hawaii, America. Feb 9-12.

3. Huang, Y. H., Huang, P. Y. and Chen, L. L.* (2020). Development of oral delivery system for aquaculture using fly maggots. Aquaculture America 2020, Hawaii, America. Feb 9-12.

2019

1.Chen, L. L.* and Huang, H. T. (2019). Application of polyamine carbon quantum dots (CQDs) to aquatic viral disease control: taking shrimp white spot syndrome (WSS) as an example. 52th Annual Meeting of the Society for Invertebrate Pathology (SIP), Valensia, Spain. Jul 28-Aug 1.

2.Gray, R. Chen, L. L.* and Lu, M. W. (2019). Recombinant VP24, a potential treatment against white spot disease in L. vannamei. 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

3.Hsiao, H. C., Yu, P. and Chen, L. L.* (2019). Screening for the proteins that can interact with grouper nervous necrosis virus coat protein (GNNVCP). 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

4.Lin, C. H. and Chen, L. L.* (2019). Investigation of protein-protein interaction between an antimicrobial peptide epinecidin-1 and proteins in Epinephelus coioides. 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

5.Huang, P. Y., Hsu, T. H., Ma, C. H. and Chen, L. L.* (2019). Evaluation and establishment of cultivation demonstration area for spiny lobster in Matsu. 黃博鈺、徐德華、馬家桓、劉德全、陳歷歷。馬祖龍蝦栽培示範區的評估及設置。台灣水產學會學術論文發表會,台北,台灣,中華民國。1月12日。

2018

1.Shih, H. Y. and Chen, L. L.* (2018). The effect of plant extract X on non-specific immune responses of white shrimp Litopenaeus vannamei. Asian Pacific Aquaculture 2018, Taipei, Taiwan, Apr 23-26.

2.Yu, P. and Chen, L. L.* (2018). Screening the protein that can interact with grouper nervous necrosis virus coat protein (GNNVCP). Asian Pacific Aquaculture 2018, Taipei, Taiwan, Apr 23-26.

2017

1.  LL Chen* (2017) Development of the oral delivery system for shrimp aquaculture using attenuated Listeria monocytogenes. The 11th Asia Pacific Marine Biotechnology Conference (APMBC). May 22-24, Hawaii, USA.

2016

1.   Chang, W. H. and Chen, L. L.* (2016). Identification and analysis of the envelope protein VP56 of shrimp white spot syndrome virus (WSSV). 11th Asian Fisheries and Aquaculture Forum (11AFAF), Bangkok, Thailand. Aug 3-7.

2.   Chen, L. L.* and Lee, Y. J. (2016). WSSV envelope protein VP51B links structural protein complexes and may mediate virus infection. 11th Asian Fisheries and Aquaculture Forum (11AFAF), Bangkok, Thailand. Aug 3-7.

3.   Lai, T. X. and Chen, L. L.* (2016). Laminin receptor is identified to interact with grouper nervous necrosis virus (NNV) coat protein. 11th Asian Fisheries and Aquaculture Forum (11AFAF), Bangkok, Thailand. Aug 3-7.

專書章節(Others)

1. Lin, H. Y., Lin, J. H. Y., Lin, H. J. and Chen, L. L.* (2021). Inhibition of white spot syndrome virus (WSSV) in Pacific white shrimp (Litopenaeus vannamei) using polyamine-modified carbon quantum dots. Methods in Molecular Biology. Springer. (In press)

2. Wang, H. C., Chiang, Y. A., Ng, T. H., Wang, H. C., Chen, L. L., Leu, J. H., Lo, C. F. (2016). Science to the rescue: interventions that help shrimp in the arms race against white spot syndrome virus (WSSV). In: Progress of shrimp and prawn aquaculture in the world (Liao, I. C., Chao, N. H., Leaño, E. M. eds). National Taiwan Ocean University, the Fisheries Society of Taiwan, Asian Fisheries Society, and World Aquaculture Society. pp. 317-336. ISBN: 978-986-04-7656-9.

3. 羅竹芳,陳歷歷,沈志忠。(2007)。生命科學講義 — 第六章遺傳學的應用 —基因工程,國立台灣師範大學生命科學系主編,pp. 113 ~ 132,國立台灣師範大學出版,中華民國九十六年十二月。

4. 陳歷歷。(2005)。現代生物學 — 第十四章生物與環境間之互動:生態學的研究,嚴震東、羅竹芳等編,pp. 199 ~ 210,臺大出版中心出版,中華民國九十四年八月。

專利

1. 陳歷歷。(2013)。治療或預防白點症病毒感染之組合物。中華民國專利發明第I384952號。專利權人:國立臺灣海洋大學,專利期間:2013年2月11日至2029年12月28日。

2. 許家愷、陳歷歷、許德根、元淑冰。(2019)。表現異源基因的系統及其用途。中華民國專利發明第I658140號。專利權人:昕穎生醫技術股份有限公司,專利期間:2019年5月1日至2035年11月11日。

3. 黃博鈺、陳歷歷、徐德華。(2020)。水產生物適用管供式凝膠飼料、其餵食系統及其方法。專利權人:國立臺灣海洋大學。專利申請案號:109136169。中華民國專利申請中。

4. 黃博鈺、陳歷歷、徐德華。(2020)。水產生物幼苗沉水培育系統及其方法。專利權人:國立臺灣海洋大學。專利申請案號:109136168。中華民國專利申請中。

5. 陳歷歷、黃博鈺、黃奕瑄。(2021)。蠅蛆載體飼料、其製造方法及其用途。專利權人:國立臺灣海洋大學。專利申請案號:110136339。中華民國專利申請中。

技術轉移

1. 周信佑、陳歷歷。(2019)。新型態產學研鏈結計畫-開發一條龍應用之新型態水產添加劑,被授權單位:國立臺灣海洋大學,臺灣。

2. 陳歷歷。(2017)。DOSTO Oregano作為免疫刺激物改善蝦類免疫及抗病力配方計畫 (DOSTO Oregano as Immunostimulant for the Improvement of Shrimp Immunity and Disease Resistance),被授權單位:DOSTOFARM GmbH,德國。

3. 陳歷歷。(2017)。以酸化劑X做為蝦飼料添加劑之配方比例與使用方式,被授權單位:永鴻國際生技股份有限公司,臺灣。

4. 陳歷歷。(2014)。治療或預防白點症病毒感染之組合物,被授權單位:昕穎生醫技術股份有限公司,臺灣。