近五年期刊論文（Publications）

2024

1. Hsu, T. K., Shih, H. Y., Huang, H. J., Hsu, J. C. K., Wang, H. C., Chen, Y. Y. and Chen, L. L.* (2024). Isolation and characterization of the novel phage BP14 for lysing Vibrio parahaemolyticus and reducing virulence proteins. Aquaculture 581, 740484. (SCI) DOI: 10.1016/j.aquaculture.2023.740484

2. Kannan, J., Pang, K. L., Ho, Y. N., Hsu, P. H.* and Chen, L. L.* (2024). Comparison of antioxidant potential and metabolite analysis of marine fungi associated with the red alga Pterocladiella capillacea from Northern Taiwan. Antioxidants 13(3), 336. DOI: 10.3390/antiox13030336

2023

1. Lee, M. C., Lo, C. T., Ho, T. H., Chen, L. L., Nan, F. H., Lai, H. C., Wangkahart, E., Lee, P. T.* (2023). Assessment of Bacillus subtilis fermented Caulerpa microphysa byproduct as feed additive on the growth performance, immune regulation and disease resistance of white shrimp (Litopenaeus vannamei). Fish and Shellfish Immunology 142, 109134. (SCI) DOI: 10.1016/j.fsi.2023.109134

2. Huang, H. J., Tang, S. L., Chang, Y. C., Wang, H. C., Ng, T. H., Garmann R. F., Chen, Y. W., Huang, J. Y., Kumar, R., Chang, S. H., Wu, S. R., Chao, C. Y., Matoba, K., Iwasaki, K., Gelbart, W. M., Ko, T. P., Wang, H. J., Lo, C. F., Chen, L. L.* and Wang, H. C.* (2023). Multiple nucleocapsid structural forms of shrimp white spot syndrome virus suggests a novel viral morphogenetic pathway. International Journal of Molecular Sciences 24(8), 7525. https://doi.org/10.3390/ijms24087525

2022

1. Budi, Y. P., Lin, L. C., Chung, C. H., Chen, L. L., Jiang, Y. F.* (2022) Three-dimensional investigations of virus-associated structures in the nuclei with white spot syndrome virus (WSSV) infection in red swamp crayfish (Procambarus clarkii). Animals 12(13), 1730. DOI:10.3390/ani12131730

2. Hsu, J. C. K.#, Huang, H. T.#, Lin, H. J., Chou, H. Y., Huang, P. Y., Prachumwat, A.* and Chen, L. L.* (2022). Applying modified VP53A recombinant protein as an anti-white spot syndrome virus biological agent in Litopenaeus vannamei farming. Viruses 14(7), 1353. DOI: 10.3390/v14071353

3. Hsu, J. C. K., Hsu, T. K., Kannan, J., Wang, H. C., Tassanakajon, A. and Chen, L. L.* (2022). Diagnostic performance of a rapid test kit for white spot syndrome virus (WSSV). Aquaculture 558, 738379. DOI: 10.1016/j.aquaculture.2022.738379

2021

1. Yen, S. C., Mao, J. Y., Lin, H. Y., Huang, H. T., Harroun, S. G., Nain, A., Chang, H. T., Lin, H. Y., Chen, L. L., Huang, C. C.* and Lin, H. J. (2021). Multifunctional carbonized nanogels to treat lethal acute hepatopancreatic necrosis disease. Journal of Nanobiotechnology 19(1), 448. DOI: 10.1186/s12951-021-01194-8.

2. Huang, P. Y., Huang, Y. H., Leu, J. H. and Chen, L. L.* (2021). Feasibility study on the use of fly maggots (Musca domestica) as carriers to inhibit shrimp white spot syndrome. Life 11(8), 818. DOI: 10.3390/life11080818.

3. Lee, P. T., Huang, J., Huang, C. Y., Liu, Z. X., Yeh, H. Y., Huang, H. T., Chen, L. L., Nan, F. H. and Lee, M. C.* (2021). Phycoerythrin from Colaconema sp. has immunostimulatory effects on the whiteleg shrimp Litopenaeus vannamei and increases resistance to Vibrio parahaemolyticus and white spot syndrome virus. Animals 11(8), 2371. DOI: 10.3390/ani11082371

4. Ma, C. H. #, Huang, P. Y. #, Chang, Y. C., Pan, Y. J., Azra, M. N., Chen, L. L., and Hsu, T. H.* (2021). Improving survival of juvenile scalloped spiny lobster (Panulirus homarus) and crucifix crab (Charybdis feriatus) using shelter and live prey. Animals 11(2), 370. DOI: 10.3390/ani11020370

2020

1. Huang, P. Y., Hsiao, H. C., Wang, S. W., Lo, S. F., Lu, M. W. and Chen, L. L.* (2020). Screening for the proteins that can interact with grouper nervous necrosis virus capsid protein. Viruses, 12(9), 985. DOI: 10.3390/v12090985

2. Huang, H. T., Lin, H. J., Huang, H. J., Huang, C. C., Lin, J. H. Y.* and Chen, L. L.* (2020). Synthesis and evaluation of polyamine carbon quantum dots (CQDs) in Litopenaeus vannamei as a therapeutic agent against WSSV. Scientific Reports 10, 7343. DOI: 10.1038/s41598-020-64325-5

2017

1. Lee, Y. J. and Chen, L. L.* (2017). WSSV envelope protein VP51B links structural protein complexes and may mediate virus infection. Journal of Fish Diseases 40(4), 571-581. DOI: 10.1111/jfd.12538

2015

1. Lu, J. K.*, Chou, H. Y., Gong, H. Y., Chiou, P. P., Huang, C. W., Chen, L. L. and Wu, J. L. (2015). The marine aquaculture biotechnology status and its sustainability in Taiwan. Current Biotechnology 4(3), 311-318. DOI: 10.2174/2211550104666151016203821

2. Huang, H. T., Chan, H. L., Shih, T. Y. and Chen, L. L.* (2015). A study of the role of glucose transporter 1 (Glut1) in white spot syndrome virus (WSSV) infection. Fish and Shellfish Immunology 46(2), 305-314. DOI: 10.1016/j.fsi.2015.06.034

3. Lin, Y. C., Chen, J. C.*, Chen, Y. Y., Yeh, S. T., Chen, L. L., Huang, C. L., Hsieh, J. F. and Li, C. C. (2015). Crowding of white shrimp Litopenaeus vananmei depresses their immunity to and resistance against Vibrio alginolyticus and white spot syndrome virus. Fish and Shellfish Immunology 45(1), 104-111. DOI: 10.1016/j.fsi.2015.02.012

近五年研討會論文（Conference posters or papers）

2023

1. Hsu, J. C. K., Hsu, T. K. and Chen, L. L.* (2023). Study on the detection accuracy of field-infected shrimp with a newly developed rapid detection kit for white spot syndrome virus. 13th Asia Pacific Marine Biotechnology Conference (APMBC), Adelaide, Australia. October 2-6.

2. Huang, P. Y., Hu, S. W and Chen, L. L.* (2023). Establish a nondestructive detect technology of smooth fan lobster (Ibacus novemdentatus) gonadal maturity. 13th Asia Pacific Marine Biotechnology Conference (APMBC), Adelaide, Australia. October 2-6.

3. Kannan, J., Hsu, P. H., Pang, K. L. and Chen, L. L.* (2023). Bioprospecting and metabolite profiling of marine fungal extracts: exploring their potential as immunostimulants. 13th Asia Pacific Marine Biotechnology Conference (APMBC), Adelaide, Australia. October 2-6. 

4. Kannan, J., Hsu, P. H., Pang, K. L. and Chen, L. L.* (2023). Bioprospecting and metabolite profiling of marine fungal extracts and its cytotoxic potential in Sf 9 cell line. 2023第四屆海水魚養殖技術國際論壇暨臺灣海洋生物技術學會學術研討會。臺北，臺灣，中華民國。9月1日。

2022

1. Hsu, J. C. K. and Chen, L. L.* (2022). Comparison of performance between a rapid test kit and qPCR method for white spot syndrome virus (WSSV). The 4th Congress of the International Society of Fish & Shellfish Immunology (4th ISFSI), Bodø, Norway. December 12-15.

2. Chen, C. C., Lin, W. Y., Lu, H. Y., Zhang, Z. F., Liou, C. H., Ho, Y. N., Huang, C. W., Yang, W. C., Chen, L. L. and Gong, H. Y.* (2022). Bidens pilosa as a multifunctional additive of feedstuff to enhance disease resistance and growth performance in farmed aquatic animals. The 4th Congress of the International Society of Fish & Shellfish Immunology (4th ISFSI), Bodø, Norway. December 12-15.

3. Chen, L. L.* and Wong, Z. W. (2022). Feasibility analysis of CS60 as a shrimp potential probiotic. 13th Asian Fisheries and Aquaculture Forum (13AFAF), Tainan, Taiwan. May 31-Jun 2.

4. Huang, P. Y., Huang, Y. H., Leu, J. H. and Chen, L. L.* (2022). Feasibility study on the use of fly maggots (Musca domestica) as carriers to inhibit shrimp white spot syndrome. 13th Asian Fisheries and Aquaculture Forum (13AFAF), Tainan, Taiwan. May 31-Jun 2.

2021

1. Wong, Z. W. and Chen, L. L.* (2021). Feasibility analysis of CS60 as a shrimp potential probiotic. The Control of Aquatic Animal Diseases, virtual. Sep 10.

2020

1. Chen, L. L.* and Huang, P. Y. (2020). Screening for the proteins that can interact with grouper nervous necrosis virus capsid protein. International Conference on Marine Science and Aquaculture (icomsa), virtual. Dec 9-10.

2. Chen, L. L.* (2020). Screening for proteins that can interact with grouper nervous necrosis virus (NNV) coat protein. Aquaculture America 2020, Hawaii, America. Feb 9-12.

3. Huang, Y. H., Huang, P. Y. and Chen, L. L.* (2020). Development of oral delivery system for aquaculture using fly maggots. Aquaculture America 2020, Hawaii, America. Feb 9-12.

2019

1. Chen, L. L.* and Huang, H. T. (2019). Application of polyamine carbon quantum dots (CQDs) to aquatic viral disease control: taking shrimp white spot syndrome (WSS) as an example. 52th Annual Meeting of the Society for Invertebrate Pathology (SIP), Valensia, Spain. Jul 28-Aug 1.

2. Gray, R. Chen, L. L.* and Lu, M. W. (2019). Recombinant VP24, a potential treatment against white spot disease in L. vannamei. 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

3. Hsiao, H. C., Yu, P. and Chen, L. L.* (2019). Screening for the proteins that can interact with grouper nervous necrosis virus coat protein (GNNVCP). 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

4. Lin, C. H. and Chen, L. L.* (2019). Investigation of protein-protein interaction between an antimicrobial peptide epinecidin-1 and proteins in Epinephelus coioides. 12th Asian Fisheries and Aquaculture Forum (12AFAF), Iloilo City, Philippines. Apr 8-12.

5. Huang, P. Y., Hsu, T. H., Ma, C. H. and Chen, L. L.* (2019). Evaluation and establishment of cultivation demonstration area for spiny lobster in Matsu. 黃博鈺、徐德華、馬家桓、劉德全、陳歷歷。馬祖龍蝦栽培示範區的評估及設置。台灣水產學會學術論文發表會，台北，台灣，中華民國。1月12日。
 

專書章節（Others）

1. Lin, H. Y., Lin, J. H. Y., Lin, H. J. and Chen, L. L.* (2023). Inhibition of white spot syndrome virus (WSSV) in Pacific white shrimp (Litopenaeus vannamei) using polyamine-modified carbon quantum dots. Methods in Molecular Biology. In: Aquino de Muro, M. (eds) Virus-Host Interactions. Methods in Molecular Biology, vol 2610. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2895-9_6

2. Wang, H. C., Chiang, Y. A., Ng, T. H., Wang, H. C., Chen, L. L., Leu, J. H. and Lo, C. F. (2016). Science to the rescue: interventions that help shrimp in the arms race against white spot syndrome virus (WSSV). In: Progress of shrimp and prawn aquaculture in the world (Liao, I. C., Chao, N. H., Leaño, E. M. eds). National Taiwan Ocean University, the Fisheries Society of Taiwan, Asian Fisheries Society, and World Aquaculture Society. pp. 317-336. ISBN: 978-986-04-7656-9.

專利

1.    陳歷歷。(2013)。治療或預防白點症病毒感染之組合物。中華民國專利發明第I384952號。專利權人：國立臺灣海洋大學，專利期間：2013年2月11日至2029年12月28日。

2.    許家愷、陳歷歷、許德根、元淑冰。(2019)。表現異源基因的系統及其用途。中華民國專利發明第I658140號。專利權人：昕穎生醫技術股份有限公司，專利期間：2019年5月1日至2035年11月11日。

3.    黃博鈺、陳歷歷、徐德華。(2023)。水產生物幼苗沉水培育系統及其方法。專利權人：國立臺灣海洋大學。中華民國專利發明第I790487號。

4.    黃博鈺、陳歷歷、徐德華。(2023)。水產生物適用管供式凝膠飼料、其餵食系統及其方法。中華民國專利發明第I790488號。

5.    陳歷歷、黃博鈺、黃奕瑄。(2021)。蠅蛆載體飼料、其製造方法及其用途。專利權人：國立臺灣海洋大學。中華民國專利發明第I824307號。
 

技術轉移

1. 周信佑、陳歷歷。(2019)。新型態產學研鏈結計畫-開發一條龍應用之新型態水產添加劑，被授權單位：國立臺灣海洋大學，臺灣。

2. 陳歷歷。(2017)。DOSTO Oregano作為免疫刺激物改善蝦類免疫及抗病力配方計畫 (DOSTO Oregano as Immunostimulant for the Improvement of Shrimp Immunity and Disease Resistance)，被授權單位：DOSTOFARM GmbH，德國。

3. 陳歷歷。(2017)。以酸化劑X做為蝦飼料添加劑之配方比例與使用方式，被授權單位：永鴻國際生技股份有限公司，臺灣。

4. 陳歷歷。(2014)。治療或預防白點症病毒感染之組合物，被授權單位：昕穎生醫技術股份有限公司，臺灣。